蛋白質二級結構預測研究,從早期的簡單統計的方法GOV(1978)

開始至少有三十個年頭。在目前蛋白質結構資料仍缺乏之下,開發

預測的工具仍然有人在進行中(Tuping etc., Bioinformatics, 2009 December 9)

本篇整理目前仍提供預測服務的網站及一張各工具的簡表

(有些資料仍待補^^a)

 

1.Name    : GOR V
   Server   : http://gor.bb.iastate.edu/
   Authors : Sen TZ, Jernigan RL, Garnier J, Kloczkowski A. GOR V server for protein secondary structure prediction. Bioinformatics. 2005 Jun 1;21(11):2787-8. Epub 2005 Mar 29.

2.Name    : Jpred
   Server   : http://www.compbio.dundee.ac.uk/www-jpred/
   Authors : Cole C, Barber JD & Barton GJ. Nucleic Acids Res. 2008.

3.Name    : jufo
   Server   : http://www.meilerlab.org/index.php/servers
   Authors : Meiler, J.; Baker, D. "Coupled Prediction of Protein Secondary and Tertiary Structure" PNAS 2003, 100, 12105-12110.

4.Name    : PORTER
   Server   : http://distill.ucd.ie/porter/
   Authors : Pollastri G, McLysaght A. Porter: a new, accurate server for protein secondary structure prediction. Bioinformatics. 2005 Apr 15;21(8):1719-20. Epub 2004 Dec 7.

5.Name    : PROF
   Server   : http://www.aber.ac.uk/~phiwww/prof/
   Authors : Ouali, M., & King, R.D. 2000. Cascaded multiple classifiers for secondary structure prediction. Prot. Sci. 9: 1162-1176.

6.Name    : PSIPRED
   Server   : http://bioinf.cs.ucl.ac.uk/psipred/(2010.08.26 更新)
   Authors : Bryson K, McGuffin LJ, Marsden RL, Ward JJ, Sodhi JS. & Jones DT. (2005) Protein structure prediction servers at University College London. Nucl. Acids Res. 33(Web Server issue):W36-38.

7.Name    : SABLE
   Server   : http://sable.cchmc.org/
   Authors : A Porollo, R Adamczak, M Wagner, and J Meller, Maximum Feasibility Approach for Consensus Classifiers: Applications to Protein Structure Prediction. CIRAS, 2003

8.Name    : SAM-T08
   Server   : http://compbio.soe.ucsc.edu/SAM_T08/T08-query.html
   Authors : Karplus K. SAM-T08, HMM-based protein structure prediction. Nucleic Acids Res. 2009 Jul 1;37(Web Server issue):W492-7. Epub 2009 May 29.

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