蛋白質二級結構預測研究,從早期的簡單統計的方法GOV(1978)
開始至少有三十個年頭。在目前蛋白質結構資料仍缺乏之下,開發
預測的工具仍然有人在進行中(Tuping etc., Bioinformatics, 2009 December 9)
本篇整理目前仍提供預測服務的網站及一張各工具的簡表。
(有些資料仍待補^^a)
1.Name : GOR V
Server : http://gor.bb.iastate.edu/
Authors : Sen TZ, Jernigan RL, Garnier J, Kloczkowski A. GOR V server for protein secondary structure prediction. Bioinformatics. 2005 Jun 1;21(11):2787-8. Epub 2005 Mar 29.
2.Name : Jpred
Server : http://www.compbio.dundee.ac.uk/www-jpred/
Authors : Cole C, Barber JD & Barton GJ. Nucleic Acids Res. 2008.
3.Name : jufo
Server : http://www.meilerlab.org/index.php/servers
Authors : Meiler, J.; Baker, D. "Coupled Prediction of Protein Secondary and Tertiary Structure" PNAS 2003, 100, 12105-12110.
4.Name : PORTER
Server : http://distill.ucd.ie/porter/
Authors : Pollastri G, McLysaght A. Porter: a new, accurate server for protein secondary structure prediction. Bioinformatics. 2005 Apr 15;21(8):1719-20. Epub 2004 Dec 7.
5.Name : PROF
Server : http://www.aber.ac.uk/~phiwww/prof/
Authors : Ouali, M., & King, R.D. 2000. Cascaded multiple classifiers for secondary structure prediction. Prot. Sci. 9: 1162-1176.
6.Name : PSIPRED
Server : http://bioinf.cs.ucl.ac.uk/psipred/(2010.08.26 更新)
Authors : Bryson K, McGuffin LJ, Marsden RL, Ward JJ, Sodhi JS. & Jones DT. (2005) Protein structure prediction servers at University College London. Nucl. Acids Res. 33(Web Server issue):W36-38.
7.Name : SABLE
Server : http://sable.cchmc.org/
Authors : A Porollo, R Adamczak, M Wagner, and J Meller, Maximum Feasibility Approach for Consensus Classifiers: Applications to Protein Structure Prediction. CIRAS, 2003
8.Name : SAM-T08
Server : http://compbio.soe.ucsc.edu/SAM_T08/T08-query.html
Authors : Karplus K. SAM-T08, HMM-based protein structure prediction. Nucleic Acids Res. 2009 Jul 1;37(Web Server issue):W492-7. Epub 2009 May 29.
